Articoli su riviste


Mengoli C, Franchini M, Marano G, Vaglio S, Pupella S, Liumbruno GM. Efficacy and Safety of Fibrinogen Concentrate in Surgical Patients: A Meta-analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. 2016 Nov 14. pii: S1053-0770(16)30593-6. doi: 10.1053/j.jvca.2016.11.019.

Lieshout-Krikke RW, Domanovic D, De Kort W, Mayr W, Liumbruno GM, Pupella S, Kurz J, Knutson F, Maclennan S, Folléa G. Selection strategies for newly registered blood donors in European countries. Blood Transfus. 2016 Sep 7;15(1):20-41. doi: 10.2450/2016.0101-16. [Epub ahead of print]

International forum: an investigation of iron status in blood donors. Vuk T, Magnussen K, De Kort WFolléa G, Liumbruno GM, Schennach H, Vandewalle G, Compernolle V, Masharova N, Karakatsiani G, Argyrou I, Řeháček V, Khanirzajeva G, Castrén J, Danic B, Djoudi R, Woimant G, Mueller MM, Politis C, Vaglio S, Daugavvanaga A, Vilutytė E, Faber JC, Borg-Aquilina D, Van Den Burg P, Bokhorst A, Pogłód R, Antoniewicz-Papis J, Muon M, Burta OL, Rosochová J, Mali P, Vesga MA, Schneider K, Norda R, Anderson N. Blood Transfus. 2017;15:20-41.


Longo V, Rebulla P, Pupella S, Zolla L, Rinalducci S. Proteomic characterization of platelet gel releasate from adult peripheral and cord blood. Proteomics Clin Appl. 2016 Aug;10(8):870-82. doi: 10.1002/prca.201500126.
M Munoz, AG Acheson, M Auerbach, M Besser, O Habler, 5 H Kehlet, GM Liumbruno,

S Lasocki, P Meybohm, R Rao Baikady,T Richards, A Shander, C So-Osman,
DR Spahn and AA Klein. International consensus statement on the peri-operative
management of anaemia and iron deficiency. Anaesthesia 2017 doi:10.1111/anae.13773.

Franchini M, Liumbruno GM, Bonfanti C, Lippi G. The evolution of anticoagulant therapy. Blood Transfus. 2016 Mar;14(2):175-84. doi: 10.2450/2015.0096-15. Review

Mörtzell Henriksson M, Newman E, Witt V, Derfler K, Leitner G, Eloot S, Dhondt A, Deeren D, Rock G, Ptak J, Blaha M, Lanska M, Gasova Z, Hrdlickova R, Ramlow W, Prophet H, Liumbruno G, Mori E, Griskevicius A, Audzijoniene J, Vrielink H, Rombout S, Aandahl A, Sikole A, Tomaz J, Lalic K, Mazic S, Strineholm V, Brink B, Berlin G, Dykes J, Toss F, Axelsson CG, Stegmayr B, Nilsson T, Norda R, Knutson F, Ramsauer B, Wahlström A. Adverse events in apheresis: An update of the WAA registry data.Transfus Apher Sci. 2016 Feb;54(1):2-15. doi: 10.1016/j.transci.2016.01.003. Review.

Caraceni P, Angeli P, Prati D, Bernardi M; Italian Association for the Study of the Liver (AISF), Liumbruno GM, Bennardello F, Piccoli P, Velati C; Italian Society of Transfusion Medicine and Immunohaematology (SIMTI). AISF-SIMTI position paper: the appropriate use of albumin in patients with liver cirrhosis. Blood Transfus. 2016 Jan;14(1):8-22. doi: 10.2450/2016.0294-15.

Liumbruno GM, Vaglio S, Biancofiore G, Marano G, Mengoli C, Franchini M, Transfusion thresholds and beyond. Blood Transfus. 2016 Mar;14(2):123-5. doi: 10.2450/2016.0008-16.

Marano G, Vaglio S, Pupella S, Liumbruno GM, Franchini M. How we treat bleeding associated with direct oral anticoagulants. Blood Transfus. 2016 Jan 19:1-9. doi: 10.2450/2016.0180-15. Review.

Biancofiore G, Vaglio S, Liumbruno GM. Hydroxyethyl-starch use and PBM: a necessary update to the Italian national guidelines. Blood Transfus. 2016 May;14(2):195-6. doi: 10.2450/2016.0061-16

Pisani G, Cristiano K, Pupella S, Liumbruno GM. West Nile Virus in Europe and Safety of Blood Transfusion. Transfus Med Hemother. 2016 May;43(3):158-67. doi: 10.1159/000446219. Review.

Cicchetti A, Berrino A, Casini M, Codella P, Facco G, Fiore A, Marano G, Marchetti M, Midolo E, Minacori R, Refolo P, Romano F, Ruggeri M, Sacchini D, Spagnolo AG, Urbina I, Vaglio S, Grazzini G, Liumbruno GM. Health Technology Assessment of pathogen reduction technologies applied to plasma for clinical use. Blood Transfus. 2016 Jul;14(4):287-386. doi: 10.2450/2016.0065-16. Review.

Bruun MT, Pendry K, Georgsen J, Manzini P, Lorenzi M, Wikman A, Borg-Aquilina D, van Pampus E, van Kraaij M, Fischer D, Meybohm P, Zacharowski K, Geisen C, Seifried E, Liumbruno GM, Folléa G, Grant-Casey J, Babra P, Murphy MF. Patient Blood Management in Europe: surveys on top indications for red blood cell use and Patient Blood Management organization and activities in seven European university hospitals. Vox Sang. 2016 Aug 10. doi: 10.1111/vox.12435. [Epub ahead of print]

Liumbruno GM, Biancofiore G, Marano G, Mengoli C, Franchini M. Liberal transfusion strategy improves survival in perioperative but not in critically ill patients. Br J Anaesth. 2016 Sep;117(3):401. doi: 10.1093/bja/aew236.


Franchini M, Capuzzo E, Liumbruno GM. Lipoprotein apheresis for the treatment of elevated circulating levels of lipoprotein(a): a critical literature review. Blood Transfus. 2015 Dec 22:1-6. doi: 10.2450/2015.0163-15. Review.

Vaglio S, Prisco D, Biancofiore G, Rafanelli D, Antonioli P, Lisanti M, Andreani L, Basso L, Velati C, Grazzini G, Liumbruno GM. Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults. Blood Transfus. 2015 Dec 15:1-43. doi: 10.2450/2015.0172-15. PMID: 26710356

Bianchi M, Vaglio S, Pupella S, Marano G, Facco G, Liumbruno GM, Grazzini G. Leucoreduction of blood components: an effective way to increase blood safety? Blood Transfus. 2015 Dec 16:1-14. doi: 10.2450/2015.0154-15. PMID: 26710353

Franchini M, Liumbruno GM, Bonfanti C, Lippi G. The evolution of anticoagulant therapy. Blood Transfus. 2015 Dec 16:1-10. doi: 10.2450/2015.0096-15. PMID: 26710352

Franchini M, Capuzzo E, Liumbruno GM. Lipoprotein apheresis for the treatment of elevated circulating levels of lipoprotein(a): a critical literature review. Blood Transfus. 2015 Dec 22:1-6. doi: 10.2450/2015.0163-15. PMID: 26710351

Franchini M, Liumbruno GM, Lippi G. The prognostic value of ABO blood group in cancer patients. Blood Transfus. 2015 Nov 6:1-7. doi: 10.2450/2015.0164-15. PMID: 26674825

Marano G, Pupella S, Vaglio S, Liumbruno GM, Grazzini G. Zika virus and the never-ending story of emerging pathogens and transfusion medicine. Blood Transfus. 2015 Nov 5:1-6. doi: 10.2450/2015.0066-15. PMID: 26674815

Muñoz M, Gómez-Ramírez S, Campos A, Ruiz J, Liumbruno GM. Pre-operative anaemia: prevalence, consequences and approaches to management. Blood Transfus. 2015 Jul;13(3):370-9. doi: 10.2450/2015.0014-15. PMID: 26192787

Angheben A, Boix L, Buonfrate D, Gobbi F, Bisoffi Z, Pupella S, Gandini G, Aprili G. Chagas disease and transfusion medicine: a perspective from non-endemic countries. Blood Transfus. 2015 Oct;13(4):540-50. doi: 10.2450/2015.0040-15.

Rebulla P, Pupella S, Santodirocco M, Greppi N, Villanova I, Buzzi M, De Fazio N, Grazzini G; Italian Cord Blood Platelet Gel Study Group (see Appendix 1).  Multicentre standardisation of a clinical grade procedure for the preparation of allogeneic platelet concentrates from umbilical cord blood. Blood Transfus. 2015 Jul 31:1-7. doi: 10.2450/2015.0122-15. PMID: 26509822

Marano G, Vaglio S, Pupella S, Facco G, Catalano L, Piccinini V, Liumbruno GM, Grazzini G. Human T-lymphotropic virus and transfusion safety: does one size fit all? Transfusion 2015 DOI 10.1111/trf.13329.

G. M. Liumbruno, S. Vaglio, G. Marano, S. Pupella & G. Grazzini. “Patient Blood Management Italy”: the Italian Pathway towards Interdisciplinary and Multimodal Blood Conservation Strategies. Transfusion Medicine, 2015, 25, Suppl. 1, 13–54

Liumbruno GM, Vaglio S, Capuzzo E, Franchini M. Fibrinogen concentrate as haemostatic therapy in acquired bleeding disorders: not only a question of dosing strategies and thresholds. Blood Transfus. 2015;13:159-60. doi: 10.2450/2014.0204-14.

Zolla L, D' Alessandro A, Rinalducci S, D'Amici GM, Pupella S, Vaglio S, Grazzini G. Classic and alternative red blood cell storage strategies: seven years of "-omics" investigations. Blood Transfus. 2015;13:21-31 doi: 10.2450/2014.0053-14.


Marano G, Vaglio S, Pupella S, Facco G, Calizzani G, Candura F, Liumbruno GM, Grazzini G.  Human Parvovirus B19 and blood product safety: a tale of twenty years of improvements. Blood Transfus. 2014 Nov 13:1-13. doi: 10.2450/2014.0174-14. [Epub ahead of print]

Muñoz M, Gómez-Ramírez S, Liumbruno GM, Grazzini G. Intravenous iron and safety: is the end of the debate on the horizon?, Blood Transfus. 2014 Jul;12(3):287-9.

Liviana Catalano, Alessandra Campolongo, Maurizio Caponera, Alessandra Berzuini, Andrea Bontadini, Giuseppe Furlò, Patrizio Pasqualetti, Giancarlo M. Liumbruno Indications and organisational methods for autologous blood transfusion procedures in Italy: results of a national survey, Blood Transfus 2014; 12: 497-508 DOI 10.2450/2014.0295-13

Liumbruno G., Vaglio S., Facco G., Biancofiore G., Calizzani G., Pupella S., Grazzini G.Transfusion-related acute lung injury incidence in Italy two years after the adoption of a national proactive exclusion policy: under-diagnosing and underreporting, Minerva Anestesiologica 2014 September;80(9):1063-4

Simonetta Pupella, Giulio Pisani, Karen Cristiano, Liviana Catalano, Giuliano Grazzini, Update on West Nile virus in Italy, Blood Transfus 2014; 12: 626-7 DOI 10.2450/2014.0110-14

Marco Musumeci, Sonia Maccari, Alessia Massimi, Tonino Stati, Paola Sestili, Elisa Corritore,Augusto Pastorelli, Paolo Stacchini, Giuseppe Marano, Liviana Catalano, Iron excretion in iron dextran-overloaded mice, Blood Transfus 2014;12: 485-90 DOI 10.2450/2014.0288-13

Marano G, Vaglio S, Pupella S, Facco G, Bianchi M, Calizzani G, Candura G, Catalano L, Farina B, Lanzoni M, Piccinini V, Liumbruno GM, Grazzini G. Hepatitis E: an old infection with new implications. Blood Transfus 2014; doi:10.2450/2014.0144-14.

Muñoz M, Gómez-Ramírez S, Liumbruno GM, Grazzini G. Intravenous iron and safety: is the end of the debate on the horizon? Blood Transfus 2014; doi:10.2450/2014.0144-14.

Calizzani G, Menichini I, Candura F, Lanzoni M, Profili S, Tamburrini MR, Fortino A, Vaglio S, Marano G, Facco G, Oliovecchio E, Franchini M, Coppola A, Arcieri R, Bon C, Saia M, Nuti S, Morfini M, Liumbruno GM, Di Minno G, Grazzini G. Definition of an organisational model for the prevention and reduction of health and social impacts of inherited bleeding disorders. Blood Transfus. 2014 Apr;12 Suppl 3:s582-8. doi: 10.2450/2014.0087-14s.

Candura F
, Menichini I, Calizzani G, Giangrande P, Mannucci PM, Makris M. The methodology for defining the European standards for the certification of Haemophilia Centres in Europe.  Blood Transfus. 2014 Apr;12 Suppl 3:s519-24. doi: 10.2450/2014.0046-14s.

Makris M, Calizzani G, Fischer K, Gatt A, Gilman E, Hollingsworth R, Lambert T, Lassila R, Mannucci PM, Peyvandi F, Windyga J. The European Haemophilia Network (EUHANET). Blood Transfus. 2014 Apr;12 Suppl 3:s515-8. doi: 10.2450/2014.0008-14s.

Giangrande P, Calizzani G, Menichini I, Candura F, Mannucci PM, Makris M. The European standards of Haemophilia Centres. Blood Transfus. 2014 Apr;12 Suppl 3:s525-30. doi: 10.2450/2014.0056-14s.

Arcieri R, Molinari AC, Farace S, Mazza G, Garnero A, Calizzani G, Giordano P, Oliovecchio E, Mantovani L, Manzoli L, Giangrande P. Uncovered needs in the management of inherited bleeding disorders in Italy. Blood Transfus. 2014 Apr;12 Suppl 3:s563-6. doi: 10.2450/2014.0036-14s. 

Kodra Y, Cavazza M, Schieppati A, De Santis M, Armeni P, Arcieri R, Calizzani G, Fattore G, Manzoli L, Mantovani L, Taruscio D. The social burden and quality of life of patients with haemophilia in Italy. Blood Transfus. 2014 Apr;12 Suppl 3:s567-75. doi: 10.2450/2014.0042-14s.

Calizzani G, Candura F, Menichini I, Arcieri R, Castaman G, Lamanna A, Tamburrini MR, Fortino A, Lanzoni M, Profili S, Pupella S, Liumbruno GM, Grazzini G. The Italian institutional accreditation model for Haemophilia Centres. Blood Transfus. 2014 Apr;12 Suppl 3:s510-4. doi: 10.2450/2014.0058-14s.

Calizzani G, Makris M, Mannucci PM, Taruscio D, Grazzini G, Oleari F. Haemophilia Centre Certification Systems: optional or optimal choice for healthcare systems? Blood Transfus. 2014 Apr;12 Suppl 3:s492-4. doi: 10.2450/2014.0076-14s.

Liumbruno GM, Vaglio S, Facco G, Biancofiore G, Calizzani G, Pupella S, Grazzini G. Transfusion-related acute lung injury incidence in Italy two years after the adoption of a national proactive exclusion policy: under-diagnosing and underreporting. Minerva Anestesiol. 2014 Mar 4. [Epub ahead of print].

Varricchio L, Dell'Aversana C, Nebbioso A, Migliaccio G, Altucci L, Mai A, Grazzini G, Bieker JJ, Migliaccio AR. Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells. Int J Biochem Cell Biol. 2014 May;50:112-22. doi: 10.1016/j.biocel.2014.02.019. Epub 2014 Mar 1.

Musumeci M, Maccari S, Massimi A, Stati T, Sestili P, Corritore E, Pastorelli A, Stacchini P, Marano G, Catalano L. Iron excretion in iron dextran-overloaded mice. Blood Transfus. 2014 Jun 5:1-6.


Napoli C, Bella A, Declich S, Grazzini G, Lombardini L, Costa AN, Nicoletti L, Pompa MG, Pupella S, Russo F, Rizzo C. Integrated human surveillance systems of west nile virus infections in Italy: the 2012 experience. Int J Environ Res Public Health. 2013 Dec 13;10(12):7180-92. doi: 10.3390/ijerph10127180.

Franchini M, Liumbruno GM, Lanzoni M, Candura F, Vaglio S, Profili S, Facco G, Calizzani G, Grazzini G. Clinical use and the Italian demand for prothrombin complex concentrates. Blood Transfus. 2013 Sep;11 Suppl 4:s94-s100. doi: 10.2450/2013.015s.

Liumbruno GM, Franchini M, Lanzoni M, Candura F, Vaglio S, Profili S, Catalano L, Facco G, Pupella S, Calizzani G, Grazzini G.Clinical use and the Italian demand and for antithrombin. Blood Transfus. 2013 Sep;11 Suppl 4:s86-93. doi: 10.2450/2013.014s.

Calizzani G, Profili S, Candura F, Lanzoni M, Vaglio S, Cannata L, Liumbruno GM, Franchini M, Mannucci PM, Grazzini G. The demand for factor VIII and for factor IX and the toll fractionation product surplus management. Blood Transfus. 2013 Sep;11 Suppl 4:s64-76. doi: 10.2450/2013.011s.

Calizzani G, Vaglio S, Candura F, Profili S, Lanzoni M, Cristiano K, Tamburrini MR, Grazzini G, Oleari F. The evolution of the regulatory framework for the plasma and plasma-derived medicinal products system in Italy. Blood Transfus. 2013 Sep;11 Suppl 4:s6-s12. doi: 10.2450/2013.003s.

Candura F, Lanzoni M, Calizzani G, Profili S, Vaglio S, Pupella S, Liumbruno GM, Grazzini G. The demand for polyvalent immunoglobulins in Italy. Blood Transfus. 2013 Sep;11 Suppl 4:s45-54. doi: 10.2450/2013.009s.

Vaglio S, Calizzani G, Lanzoni M, Candura F, Profili S, Catalano L, Cannata L, Liumbruno GM, Grazzini G. The demand for human albumin in Italy. Blood Transfus. 2013 Sep;11 Suppl 4:s26-32. doi: 10.2450/2013.006s.

Grazzini G, Mannucci PM, Oleari F. Plasma-derived medicinal products: demand and clinical use. Blood Transfus. 2013 Sep;11 Suppl 4:s2-5. doi: 10.2450/2013.002s.

Grazzini G, Ceccarelli A, Calteri D, Catalano L, Calizzani G, Cicchetti A. Sustainability of a public system for plasma collection, contract fractionation and plasma-derived medicinal product manufacturing. Blood Transfus. 2013 Sep;11 Suppl 4:s138-47. doi: 10.2450/2013.020s.

Lanzoni M, Biffoli C, Candura F, Calizzani G, Vaglio S, Grazzini G. Plasma-derived medicinal products in Italy: information sources and flows. Blood Transfus. 2013 Sep;11 Suppl 4:s13-7. doi: 10.2450/2013.004s.

Calizzani G, Profili S, Candura F, Lanzoni M, Vaglio S, Cannata L, Catalano L, Chianese R, Liumbruno GM, Grazzini G. Plasma and plasma-derived medicinal product self-sufficiency: the Italian case. Blood Transfus. 2013 Sep;11 Suppl 4:s118-31. doi: 10.2450/2013.018s.

Lanzoni M, Candura F, Calizzani G, Biffoli C, Grazzini G. Public expenditure for plasma-derived and recombinant medicinal products in Italy. Blood Transfus. 2013 Sep;11 Suppl 4:s110-7. doi: 10.2450/2013.017s.

Coppola A, Tagliaferri A, Calizzani G, Candura F, Franchini M, Ruosi C, Grazzini G, Di Minno G. Clinical use and the Italian demand for activated prothrombin complex and activated recombinant factor VII concentrates. Blood Transfus. 2013 Sep;11 Suppl 4:s101-9. doi: 10.2450/2013.016s.

Maffi D, Pasquino MT, Mandarino L, Tortora P, Girelli G, Meo D, Grazzini G, Caprari P. Glucose-6-phosphate dehydrogenase deficiency in Italian blood donors: prevalence and molecular defect characterization. Vox Sang. 2013 Oct 18. doi: 10.1111/vox.12096. [Epub ahead of print].

Vaglio S, Calizzani G, Grazzini G, Lanzoni M, Liumbruno GM. Italian albumin usage (or misusage?). Eur J Intern Med. 2013 Oct 11. pii: S0953-6205(13)00956-4. doi: 10.1016/j.ejim.2013.09.010. [Epub ahead of print].

Pupella S, Pisani G, Cristiano K, Catalano LGrazzini G. West Nile virus in the transfusion setting with a special focus on Italian preventive measures adopted in 2008-2012 and their impact on blood safety. Blood Transfus. 2013 Oct;11(4):563-74. doi: 10.2450/2013.0077-13. Epub 2013 Oct 23.

Calizzani G, Vaglio S, Vetrugno V, Delbò M, Pani L, Grazzini G. Management of notifications of donors with Creutzfeldt-Jakob disease (post-donation information). Blood Transfus. 2013 Oct 2:1-6. doi: 10.2450/2013.0035-13. [Epub ahead of print].

Suligoi B, Pupella S, Regine V, Raimondo M, Velati C, Grazzini G. Changing blood donor screening criteria from permanent deferral for men who have sex with men to individual sexual risk assessment: no evidence of a significant impact on the human immunodeficiency virus epidemic in Italy. Blood Transfus. 2013 Jul;11(3):441-8. doi: 10.2450/2013.0162-12. Epub 2013 Jun 14.

Calizzani G, Vaglio S, Arcieri R, Menichini I, Tagliaferri A, Antoncecchi S, Carloni MT, Breda A, Santagostino E, Ghirardini A, Tamburrini MR, Morfini M, Mannucci PM, Grazzini G. Models for institutional and professional accreditation of haemophilia centres in Italy. Haemophilia. 2013 Jul;19(4):e248-55. doi: 10.1111/hae.12141. Epub 2013 Apr 5.

Arcieri R, Molinari AC, Farace S, Mazza G, Garnero A, Calizzani G, Giordano P, Oliovecchio E, Mantovani L, Manzoli L, Giangrande P. Present and future challenges in the treatment of haemophilia: the patient's perspective. Blood Transfus. 2013 Sep;11 Suppl 4:s82-5. doi: 10.2450/2013.013s.

Lombardini L, Bosi A, Grosz S, Pamphilon D, Fehily D, Mareri M, Carella C, Pia Mariani M, Pupella S, Grazzini G, Costa AN. Haematopoietic stem cell transplantation: a comparison between the accreditation process performed by competent authorities and JACIE in Italy. Vox Sang. 2013 Aug;105(2):174-6. doi: 10.1111/vox.12026. Epub 2013 Feb 9.

Aprili G, Bosi A, Lombardini L, Pupella S, Vassanelli A. Recommendations for managing the donation of haematopoietic stem cells from related and unrelated donors for allogeneic transplantation. Blood Transfus. 2013 Apr;11(2):296-304. doi: 10.2450/2012.0083-12. Epub 2013 Jan 23.

Musumeci M, Maccari S, Sestili P, Massimi A, Corritore E, Marano G, Catalano L. The C57BL/6 genetic background confers cardioprotection in iron-overloaded mice. Blood Transfus. 2013 Jan;11(1):88-93.


Pisani G, Pupella S, Cristiano K, Marino F, Simeoni M, Luciani F, Scuderi G, Sambri V, Rossini G, Gaibani P, Pierro A, Wirz M, Grazzini G. Detection of West Nile virus RNA (lineages 1 and 2) in an external quality assessment programme for laboratories screening blood and blood components for West Nile virus by nucleic acid amplification testing. Blood Transfus. 2012 Oct;10(4):515-20. doi: 10.2450/2012.0036-12.

Grazzini G, Vaglio S. Red blood cell storage lesion and adverse clinical outcomes: post hoc ergo propter hoc? Blood Transfus. 2012 May;10 Suppl 2:s4-6. doi: 10.2450/2012.002S.

WHO Expert Group. Expert Consensus Statement on achieving self-sufficiency in safe blood and blood products, based on voluntary non-remunerated blood donation (VNRBD). Vox Sang. 2012 Nov;103(4):337-42. doi: 10.1111/j.1423-0410.2012.01630.x. Epub 2012 Jun 13.

Calizzani G, Arcieri R. Clinical and organisational aspects of haemophilia care: the patients' view. Blood Transfus. 2012 Jan;10(1):110-1. doi: 10.2450/2011.0043-11.

Migliaccio AR, Grazzini G, Hillyer CD. Ex vivo generated red cells as transfusion products. Stem Cells Int. 2012;2012:615412. doi: 10.1155/2012/615412. Epub 2012 Apr 18.

Whitsett C, Vaglio S, Grazzini G. Alternative blood products and clinical needs in transfusion medicine. Stem Cells Int. 2012;2012:639561. doi: 10.1155/2012/639561. Epub 2012 Apr 8.


Pisani G, Pupella S, Marino F, Gaggioli A, Sambri V, Rossini G, Wirz M, Grazzini G. Interlaboratory study to evaluate the performance of laboratories involved in West Nile virus RNA screening of blood and blood components by nucleic acid amplification testing in Italy. Blood Transfus. 2011 Oct;9(4):425-9. doi: 10.2450/2011.0025-11.

Benjamin RJ, Bianco C, Goldman M, Seed CR, Yang H, Lee J, Keller AJ, Wendel S, Biagini S, Murray J, Devine DV, Zhu Y, Turek P, Moftah FM, Kullaste R, Pillonel J, Danic B, Bigey F, Folléa G, Seifried E, Mueller MM, Lin CK, Makroo RN, Grazzini G, Pupella S, Velati C, Tadokoro K, Bravo Lindoro A, D'Artote González A, Giner VT, Flanagan P, Olaussen RW, Letowska M, Rosiek A, Poglod R, Zhiburt E, Mali P, Rozman P, Gulube S, Castro Izaguirre E, Ekermo B, Barnes SM, McLaughlin L, Eder AF, Panzer S, Reesink HW. Deferral of males who had sex with other males. Vox Sang. 2011 Nov;101(4):339-67. doi: 10.1111/j.1423-0410.2011.01489.x.

Liumbruno GM, Panetta V, Bonini R, Chianese R, Fiorin F, Lupi MA, Tomasini I, Grazzini G. Institutional authorisation and accreditation of Transfusion Services and Blood Donation Sites: results of a national survey. Blood Transfus. 2011 Oct;9(4):436-54. doi: 10.2450/2011.0025-10. Epub 2011 May 31.

Makris M, Calizzani G, Fischer K, Gilman EA, Hay CR, Lassila R, Lambert T, Ludlam CA, Mannucci PM. EUHASS: The European Haemophilia Safety Surveillance system. Thromb Res. 2011 Jan;127 Suppl 2:S22-5. doi: 10.1016/S0049-3848(10)70150-X.

Capone F, Lombardini L, Pupella S, Grazzini G, Costa AN, Migliaccio G. Cord blood stem cell banking: a snapshot of the Italian situation. Transfusion. 2011 Sep;51(9):1985-94. doi: 10.1111/j.1537-2995.2011.03089.x. Epub 2011 Mar 18.

Rinalducci S, D'Amici GM, Blasi B, Vaglio S, Grazzini G, Zolla L. Peroxiredoxin-2 as a candidate biomarker to test oxidative stress levels of stored red blood cells under blood bank conditions. Transfusion. 2011 Jul;51(7):1439-49. doi: 10.1111/j.1537-2995.2010.03032.x. Epub 2011 Jan 28.

Musumeci M, Maccari S, Corritore E, Massimi A, Stati T, Marano G, Catalano L. Signaling pathway-focused gene expression profiling in pressure overloaded hearts. Ann Ist Super Sanita. 2011;47(3):290-295.


D'Amici GM, Timperio AM, Gevi F, Grazzini G, Zolla L. Recombinant clotting factor VIII concentrates: Heterogeneity and high-purity evaluation. Electrophoresis. 2010 Aug;31(16):2730-9. doi: 10.1002/elps.201000216.

Devine DV, Reesink HW, Panzer S, Irving DO, Körmöczi GF, Mayr WR, Blais Y, Zhu Y, Qian K, Zhu Z, Greinacher A, Grazzini G, Pupella S, Catalano L, Vaglio S, Liumbruno GM, Smeenk JW, Josemans EA, Briët E, Letowska M, Lachert E, Antoniewicz-Papis J, Brojer E, Gulliksson H, Scott M, Williamson L, Prowse C, AuBuchon JP, López JA, Hoffman P, Busch MP, Norris PJ, Tomasulo P, Dodd RY. Research and development. Vox Sang. 2010 Nov;99(4):382-401. doi: 10.1111/j.1423-0410.2010.01379.x.  Epub 2010 Aug 18.

D'Alessandro A, Grazzini G, Giardina B, Zolla L. In silico analyses of proteomic data suggest a role for heat shock proteins in umbilical cord blood hematopoietic stem cells. Stem Cell Rev. 2010 Dec;6(4):532-47. doi: 10.1007/s12015-010-9180-z.

Pisani G, Cristiano K, Marino F, Luciani F, Bisso GM, Gaggioli A, Mele C, Pupella S, Grazzini G, Wirz M. External quality assessment programmes for detection of HCV RNA, HIV RNA and HBV DNA in plasma: improved proficiency of the participants observed over a 2-year period. Vox Sang. 2010 Nov;99(4):319-24. doi: 10.1111/j.1423-0410.2010.01370.x.

Timperio AM, Gevi F, Grazzini G, Vaglio S, Zolla L. Comparison among plasma-derived clotting factor VIII by using monodimensional gel electrophoresis and mass spectrometry. Blood Transfus. 2010 Jun;8 Suppl 3:s98-104. doi: 10.2450/2010.016S.

Grazzini G. Transfusion medicine and proteomics: an alliance for blood quality and safety. Blood Transfus. 2010 Jun;8 Suppl 3:s6-8. doi: 10.2450/2010.002S.

D'Alessandro A, Liumbruno G, Grazzini G, Zolla L. Red blood cell storage: the story so far. Blood Transfus. 2010 Apr;8(2):82-8. doi: 10.2450/2009.0122-09. Review.

Reesink HW, Panzer S, Gonzalez CA, Lena N, Muntaabski P, Gimbatti S, Wood E, Lambermont M, Deneys V, Sondag D, Alport T, Towns D, Devine D, Turek P, Auvinen MK, Koski T, Lin CK, Lee CK, Tsoi WC, Lawlor E,Grazzini G, Piccinini V, Catalano L, Pupella S, Kato H, Takamoto S, Okazaki H, Hamaguchi I, Wiersum-Osselton JC, Van Tilborgh AJ, Zijlker-Jansen PY, Mangundap KM, Schipperus MR, Dinesh D, Flanagan P, Flesland Ø, Steinsvåg CT, Espinosa A, Letowska M, Rosiek A, Antoniewicz-Papis J, Lachert E, Koh MB, Alcantara R, Corral Alonso M, Muñiz-Diaz E. Haemovigilance for the optimal use of blood products in the hospital. Vox Sang. 2010 Oct;99(3):278-93. doi: 10.1111/j.1423-0410.2010.01323.x.

Liumbruno G, D'Alessandro A, Grazzini G, Zolla L. How has proteomics informed transfusion biology so far? Crit Rev Oncol Hematol. 2010 Dec;76(3):153-72. doi: 10.1016/j.critrevonc.2010.01.009. Epub 2010 Feb 8. Review.

Liumbruno GM, D'Alessandro A, Rea F, Piccinini V, Catalano L, Calizzani G, Pupella S, Grazzini G. The role of antenatal immunoprophylaxis in the prevention of maternal-foetal anti-Rh(D) alloimmunisation. Blood Transfus. 2010 Jan;8(1):8-16. doi: 10.2450/2009.0108-09. Review.


Hess JR, Grazzini G. Blood proteomics and transfusion safety. J Proteomics. 2010 Jan 3;73(3):365-7. doi: 10.1016/j.jprot.2009.09.019. Epub 2009 Oct 1.

Liumbruno G, D'Alessandro A, Grazzini G, Zolla L. Blood-related proteomics. J Proteomics. 2010 Jan 3;73(3):483-507. doi: 10.1016/j.jprot.2009.06.010. Epub 2009 Jun 27. Review.

D'Alessandro A, Liumbruno G, Grazzini G, Pupella S, Lombardini L, Zolla L. Umbilical cord blood stem cells: towards a proteomic approach. J Proteomics. 2010 Jan 3;73(3):468-82. doi: 10.1016/j.jprot.2009.06.009. Epub 2009 Jun 24. Review.

Liumbruno GM, Catalano L, Piccinini V, Pupella S, Grazzini G. Reduction of the risk of bacterial contamination of blood components through diversion of the first part of the donation of blood and blood components. Blood Transfus. 2009 Apr;7(2):86-93. doi: 10.2450/2008.0026-08. Review.

Pattacini C, Rivolta GF, Di Perna C, Riccardi F, Tagliaferri A; Haemophilia Centres Network of Emilia-Romagna Region. A web-based clinical record 'xl'Emofilia' for outpatients with haemophilia and allied disorders in the Region of Emilia-Romagna: features and pilot use. Haemophilia. 2009 Jan;15(1):150-8. doi: 10.1111/j.1365-2516.2008.01921.x.


Brand A, Rebulla P, Engelfriet CP, Reesink HW, Beguin Y, Baudoux E, Kögler G, Ebrahimi M, Grazzini G, Costa AN, Bosi A, Sacchi N, Lombardini L, Pupella S, Lecchi L, Garcidueñas ED, van Beckhoven JM, de Wit HJ, Fibbe WE, Zhiburt EB, Bart T, Beksaç M, Navarrete C, Regan F. Cord blood banking. Vox Sang. 2008 Nov;95(4):335-48. doi: 10.1111/j.1423-0410.2008.01106.x.

Grazzini G, Liumbruno GM, Pupella S, Silvestri AR, Randi V, Pascarelli N, Zucchelli P, Di Caro A, Spataro N, D'Angelo E, Sambri V. West Nile virus in Italy: a further threat to blood safety, a further challenge to the blood system. Blood Transfus. 2008 Oct;6(4):235-7.

Liumbruno GM, Calteri D, Petropulacos K, Mattivi A, Po C, Macini P, Tomasini I, Zucchelli P, Silvestri AR, Sambri V, Pupella S, Catalano L, Piccinini V, Calizzani G, Grazzini G. The Chikungunya epidemic in Italy and its repercussion on the blood system. Blood Transfus. 2008 Oct;6(4):199-210.

Grazzini G. Clinical appropriateness of blood component transfusion: regulatory requirements and standards set by the Scientific Society in Italy. Blood Transfus. 2008 Oct;6(4):186-90. Review.

Liumbruno GM, Sodini ML, Grazzini G; Tuscan Transfusion System. Recommendations from the Tuscan Transfusion System on the appropriate use of solvent/detergent-inactivated fresh-frozen plasma. Blood Transfus. 2008 Jan;6(1):25-36.

Liumbruno G, D'Amici GM, Grazzini G, Zolla L. Transfusion medicine in the era of proteomics. J Proteomics. 2008 Apr 30;71(1):34-45. doi: 10.1016/j.jprot.2008.02.004. Epub 2008 Mar 5. Review.

Grazzini G, Rossi G, Rafanelli D, Gambelli D, Farina C, Mori F, Zucchelli P, Marchiori G, Breda A, Liumbruno GM. Quality control of recovered plasma for fractionation: an extensive Italian study. Transfusion. 2008 Jul;48(7):1459-68. doi: 10.1111/j.1537-2995.2008.01709.x. Epub 2008 Apr 23.

  • Il sangue 'artificiale' non sostituisce quello donato

    Il metodo per produrre globuli rossi a partire da staminali descritto dall’università di Bristol e pubblicato sulla rivista Nature Communications è ‘interessante’ per applicazioni ‘di nicchia’ ma non sostituisce il sangue donato. Lo afferma Simonetta Pupella, direttore dell’area sanitaria e dei sistemi ispettivi del Centro Nazionale Sangue commentando lo studio.


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